CLORGYLINE HYDROCHLORIDE

  • Name: CLORGYLINE HYDROCHLORIDE
  • CAS: 17780-75-5
  • Purity: 99%
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Details

High Quality Chinese Manufacturer supply 17780-75-5 CLORGYLINE HYDROCHLORIDE

  • Molecular Formula: C13H15 Cl2 N O . Cl H
  • Molecular Weight: 308.635
  • Vapor Pressure: 2.1E-05mmHg at 25°C 
  • Boiling Point: 361.3°Cat760mmHg 
  • Flash Point: 172.3°C 
  • PSA： 12.47000 
  • Density: g/cm3 
  • LogP: 4.12930 

CLORGYLINE HYDROCHLORIDE(Cas 17780-75-5) Usage

Biochem/physiol Actions

MAO-A inhibitor.

references

[1]. abdelhafez om, amin km, ali hi, et al. synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase a inhibitors. j med chem. 2012 dec 13;55(23):10424-36.[2]. mazouz f, gueddari s, burstein c, et al. 5-[4-(benzyloxy)phenyl]-1,3,4-oxadiazol-2(3h)-one derivatives and related analogues: new reversible, highly potent, and selective monamine oxidase type b inhibitors. j med chem. 1993 apr 30;36(9):1157-67.[3]. garcia-miralles m, ooi j, ferrari bardile c, et al. treatment with the mao-a inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of huntington disease. exp neurol. 2016 apr;278:4-10.

InChI:InChI=1/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

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